Company Filing History:
Years Active: 2013-2015
Title: Innovations of Ying-Jan Wang in Breast Cancer Research
Introduction
Ying-Jan Wang is a notable inventor based in Taipei, Taiwan. He has made significant contributions to the field of breast cancer research, particularly in understanding the mechanisms of nicotine-derived compounds and their effects on cancer cells. With a total of 2 patents, his work is pivotal in developing potential treatments for breast cancer.
Latest Patents
Wang's latest patents include a method for identifying candidate compounds that may inhibit α9-nAChR overexpression or estrogen receptor-dependent transcription in nicotine-derived-compound-induced breast cancer cells. This invention focuses on methods that utilize an activating protein 1 (AP1) polypeptide to identify compounds that can inhibit the proliferation of cancer cells. His research has revealed that α9-nAChR has an AP1-binding site, which is crucial for understanding how estrogen receptors interact with the α9-nAChR promoter, thereby influencing cancer cell responses to nicotine and estrogen.
Another significant patent involves the development of small interfering RNAs (siRNAs) aimed at inhibiting the expression of α9-nAChR to combat breast cancer. This invention addresses the overexpression and activation of α9-nAChR, which are linked to tumorigenesis in breast cancer. The methods proposed in this patent provide innovative approaches for the prevention, inhibition, and treatment of malignant progression in breast cancer.
Career Highlights
Ying-Jan Wang is affiliated with Taipei Medical University, where he continues to advance his research in cancer biology. His work is characterized by a strong focus on the molecular mechanisms underlying breast cancer, particularly in relation to nicotine exposure.
Collaborations
Wang collaborates with esteemed colleagues, including Chia-Hwa Lee and Ching-Shyang Chen, to further enhance the impact of his research. Their combined expertise contributes to the development of innovative solutions in cancer treatment.
Conclusion
Ying-Jan Wang's contributions to breast cancer research through his patents and collaborations highlight the importance of innovative approaches in combating this disease. His work not only advances scientific understanding but also paves the way for potential therapeutic interventions.