The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 29, 2013
Filed:
Feb. 14, 2011
Chia-hwa Lee, Taipei, TW;
Ching-shui Huang, Taipei, TW;
Ching-shyang Chen, Taipei, TW;
Shih-hsin Tu, Taipei, TW;
Ying-jan Wang, Taipei, TW;
Yu-jia Chang, Taipei, TW;
Ka-wai Tam, Taipei, TW;
Po-li Wei, Taipei, TW;
Tzu-chun Cheng, Taipei, TW;
Jan-show Chu, Taipei, TW;
Li-ching Chen, Taipei, TW;
Chih-hsiung Wu, Taipei, TW;
Yuan-soon Ho, Taipei, TW;
Chia-Hwa Lee, Taipei, TW;
Ching-Shui Huang, Taipei, TW;
Ching-Shyang Chen, Taipei, TW;
Shih-Hsin Tu, Taipei, TW;
Ying-Jan Wang, Taipei, TW;
Yu-Jia Chang, Taipei, TW;
Ka-Wai Tam, Taipei, TW;
Po-Li Wei, Taipei, TW;
Tzu-Chun Cheng, Taipei, TW;
Jan-Show Chu, Taipei, TW;
Li-Ching Chen, Taipei, TW;
Chih-Hsiung Wu, Taipei, TW;
Yuan-Soon Ho, Taipei, TW;
Taipei Medical University, Taipei, TW;
Abstract
The invention found that overexpression and activation of α9-nAChR are associated with tumorigenesis of breast cancer and create a number of small interfering RNAs to inhibit the expression of α9-nAChR so as to inhibit breast cancer. Therefore, the invention provides small interfering RNAs (siRNAs) for inhibiting expression of α9-nAChR so as to inhibit breast cancer, methods to prevent/inhibit/treat malignant progression of nicotine-derived-compound-induced breast cancer and method of determining malignant level of such breast cancer.