Company Filing History:
Years Active: 2013-2015
Title: Shih-Hsin Tu: Innovator in Breast Cancer Research
Introduction
Shih-Hsin Tu is a prominent inventor based in Taipei, Taiwan. He has made significant contributions to the field of breast cancer research, particularly in understanding the mechanisms of nicotine-derived compounds and their effects on cancer cells. With a total of 2 patents, his work is paving the way for innovative treatments and preventive measures against breast cancer.
Latest Patents
One of Shih-Hsin Tu's latest patents is a method of identifying a candidate compound that may inhibit α9-nAChR overexpression or estrogen receptor-dependent transcription in nicotine-derived-compound-induced breast cancer cells. This invention relates to methods that utilize an activating protein 1 (AP1) polypeptide to identify compounds that can inhibit the proliferation of cancer cells. The findings indicate that α9-nAChR has an AP1-binding site, which plays a crucial role in the response to both endogenous and exogenous stimulation.
Another significant patent involves small interfering RNAs (siRNAs) designed to inhibit the expression of α9-nAChR, thereby preventing the malignant progression of breast cancer. This invention highlights the association between α9-nAChR overexpression and tumorigenesis in breast cancer, providing methods for prevention, inhibition, and treatment of this disease.
Career Highlights
Shih-Hsin Tu is affiliated with Taipei Medical University, where he conducts his research and develops innovative solutions for breast cancer treatment. His work is characterized by a strong focus on the molecular mechanisms underlying cancer progression, particularly in relation to nicotine exposure.
Collaborations
Shih-Hsin Tu collaborates with notable colleagues, including Chia-Hwa Lee and Ching-Shyang Chen. These partnerships enhance the research efforts and contribute to the advancement of knowledge in the field of cancer research.
Conclusion
Shih-Hsin Tu's innovative work in breast cancer research exemplifies the importance of scientific inquiry in developing effective treatments. His patents reflect a commitment to addressing critical health challenges and improving patient outcomes.