Taipei, Taiwan

Yih-Shyun Edmond Cheng

USPTO Granted Patents = 5 

 

Average Co-Inventor Count = 4.8

ph-index = 4

Forward Citations = 79(Granted Patents)


Company Filing History:


Years Active: 2011-2019

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5 patents (USPTO):Explore Patents

Title: Innovations of Yih-Shyun Edmond Cheng in the Field of Sialidase Research

Introduction

Yih-Shyun Edmond Cheng is a prolific inventor based in Taipei, Taiwan, who has made significant contributions in the realm of biochemistry and pharmaceuticals. With a total of five patents to his name, Cheng's work primarily focuses on developing novel compounds for medical applications, particularly in combating influenza.

Latest Patents

Cheng's latest patents showcase his innovative approach to addressing viral infections and enzyme inhibition. One notable patent is for "Cell-permeable probes for identification and imaging of sialidases." This invention involves compounds that serve as sialidase inhibitors, particularly an alkynyl-3-fluorosialyl fluoride. Among these compounds is DFSA, which functions by trapping a 3-fluorosialylenzyme intermediate, allowing for the isolation and identification of sialidases.

Another groundbreaking patent is titled "Enhanced anti-influenza agents conjugated with anti-inflammatory activity." This patent introduces dual-targeted, bifunctional anti-influenza drugs formed through the conjugation with anti-inflammatory agents. The exemplary drugs include caffeic acid-bearing zanamivir conjugates, which exhibit greater efficacy than traditional combination therapies against lethal H1N1 and H5N1 influenza virus infections in mice.

Career Highlights

Cheng's contributions to the field have been recognized through his patents and his tenure at Academia Sinica, a prestigious research institution in Taiwan. There, he focuses on innovative research initiatives aimed at understanding and combating various viral infections and inflammatory responses.

Collaborations

Throughout his career, Cheng has worked closely with renowned colleagues such as Chi-Huey Wong and Jim-Min Fang. These collaborations have fostered an environment of innovation and have led to advancements in their respective fields.

Conclusion

With his impressive track record of patents and collaborative efforts, Yih-Shyun Edmond Cheng stands as a significant figure in the field of biochemistry and pharmaceutical research. His innovative solutions not only enhance our understanding of viral mechanisms but also pave the way for developing more effective therapeutic agents to address public health challenges.

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