Location History:
- Beaverton, OR (US) (2017)
- Cypress, CA (US) (1995 - 2022)
- Los Angeles, CA (US) (2016 - 2024)
Company Filing History:
6 out of 1,629 
3 out of 597 
2 out of 3 Years Active: 1995-2024
Title: Innovations in Cancer Treatment by Yi Zhang
Introduction
Yi Zhang is a prominent inventor based in Cypress, CA, who has made significant contributions to the field of cancer treatment. With a total of 10 patents to his name, his work focuses on developing compounds and methods that enhance the effectiveness of existing cancer therapies. His innovative approaches aim to overcome resistance that cancer cells often develop against conventional treatments.
Latest Patents
One of Yi Zhang's latest patents involves compounds and methods to sensitize cancer cells to cisplatin. This invention relates to sensitizer compounds that can make cancer and pre-cancerous cells more receptive to treatment with resistance-prone therapeutics. The patent describes the use of conjugates of specific esters or amides of Near Infrared Dyes as sensitizers. These sensitizers can be combined with various therapeutic agents, including cisplatin, simvastatin, and artemisinin, to improve treatment outcomes for cancers that typically develop resistance.
Another significant patent by Yi Zhang focuses on sensitizing cancer cells to tyrosine kinase inhibitors (TKIs). This invention outlines the use of TKI-sensitizing compounds in combination with TKIs like gefitinib or icotinib. The administration regimes proposed in this patent aim to enhance the effectiveness of TKI treatments, particularly for cancers that are known to develop resistance, such as lung and pancreatic cancer.
Career Highlights
Yi Zhang has worked with esteemed institutions, including the University of Southern California and Cedars-Sinai Medical Center. His experience in these organizations has allowed him to collaborate with leading experts in the field and contribute to groundbreaking research in cancer therapy.
Collaborations
Some of Yi Zhang's notable coworkers include Mark Salman Humayun and Chongwu Zhou. Their collaborative efforts have further advanced the research and development of innovative cancer treatments.
Conclusion
Yi Zhang's contributions to cancer treatment through his innovative patents demonstrate his commitment to improving therapeutic outcomes for patients. His work in sensitizing cancer cells to existing treatments is paving the way for more effective cancer therapies.