Company Filing History:
Years Active: 2017-2018
Title: Innovations in Vaccine Development by Yi-Tsui Chiu
Introduction
Yi-Tsui Chiu is a prominent inventor based in Hsinchu County, Taiwan. He has made significant contributions to the field of vaccine development, particularly in therapeutic vaccines for hepatitis B. With a total of 2 patents to his name, Chiu's work is paving the way for advancements in immunology and infectious disease treatment.
Latest Patents
Chiu's latest patents include innovative approaches to hepatitis B therapeutic vaccines. One patent discloses a fusion protein designed for use as a hepatitis B therapeutic vaccine. This fusion protein consists of an antigen-presenting cell (APC)-binding domain or a CD91 receptor-binding domain, a protein transduction domain, and an antigen that includes a hepatitis B virus X protein deletion mutant. The protein transduction domain is a fusion polypeptide that incorporates a T cell sensitizing signal-transducing peptide, a linker, and a translocation peptide. The APC-binding domain or the CD91 receptor-binding domain is positioned at the N-terminus of the fusion protein, while the antigen is located at the C-terminus of the protein transduction domain.
Another patent focuses on vaccine compositions that aim to induce enhanced antigen-specific T cell-mediated immune responses. This composition includes a therapeutically effective amount of an immunogenic protein, a saponin-based adjuvant, and a Toll-like receptor (TLR) agonist adjuvant. The adjuvants selected for this composition include GPI-0100, Quil A, QS-21, monophosphoryl lipid A (MPL), and CpG1826.
Career Highlights
Chiu is currently associated with Thevax Genetics Vaccine Co., Ltd., where he continues to innovate in the field of vaccine research and development. His work is crucial in addressing the challenges posed by infectious diseases, particularly hepatitis B.
Collaborations
Chiu collaborates with notable colleagues, including Chia-Mao Wu and Jiun-Ming Wu. Their combined expertise enhances the research and development efforts at Thevax Genetics Vaccine Co., Ltd.
Conclusion
Yi-Tsui Chiu's contributions to vaccine development, particularly in therapeutic vaccines for hepatitis B, highlight his role as an influential inventor in the field. His innovative patents and collaborations are essential in advancing
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.