The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 03, 2017

Filed:

Feb. 24, 2016
Applicant:

Thevax Genetics Vaccine Co., Ltd., Taipei, TW;

Inventors:

Chia-Mao Wu, Hsinchu County, TW;

Jiun-Ming Wu, Hsinchu County, TW;

Yi-Tsui Chiu, Hsinchu County, TW;

Yin-Ching Lin, Hsinchu County, TW;

Hsien-Kai Chuang, Hsinchu County, TW;

Fu-Tan Hsieh, Hsinchu County, TW;

Kuan-Ming Chen, Hsinchu County, TW;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/39 (2006.01); A61K 38/16 (2006.01); A61K 38/17 (2006.01); A61K 39/12 (2006.01); C12N 7/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/39 (2013.01); A61K 38/164 (2013.01); A61K 38/1774 (2013.01); A61K 39/12 (2013.01); C12N 7/00 (2013.01); A61K 2039/545 (2013.01); A61K 2039/55511 (2013.01); A61K 2039/55561 (2013.01); A61K 2039/55572 (2013.01); A61K 2039/55577 (2013.01); A61K 2039/585 (2013.01); A61K 2039/6031 (2013.01); A61K 2039/6037 (2013.01); C12N 2710/20033 (2013.01); C12N 2710/20034 (2013.01); C12N 2710/20071 (2013.01);
Abstract

Vaccine compositions for use in inducing enhanced antigen-specific T cell-mediated immune responses in a subject in need thereof are disclosed. The composition comprises (a) a therapeutically effective amount of an immunogenic protein comprising at least an antigen of a pathogen; (b) a saponin-base adjuvant selected from the group consisting of GPI-0100, Quil A, QS-21; and (c) a Toll-like receptor (TLR) agonist adjuvant selected from the group consisting of monophosphoryl lipid A (MPL), and CpG1826.


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