Company Filing History:
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Years Active: 2007-2009
Title: Yasuhiro Takegawa: Innovator in Glycoprotein Synthesis and Mass Spectrometry
Introduction
Yasuhiro Takegawa is a notable inventor based in Sapporo, Japan. He has made significant contributions to the fields of glycoprotein synthesis and mass spectrometry. With a total of 3 patents to his name, Takegawa's work has advanced the understanding and application of complex biochemical processes.
Latest Patents
One of Takegawa's latest patents focuses on the synthesis of the core sugar chain structure of asparagine-linked glycoproteins. This invention aims to chemically synthesize the trisaccharide moiety at the reducing end of the core sugar chain structure. By utilizing a highly inexpensive natural polysaccharide with a mannose β-1,4-bond as the starting material, a β-1,4-glycoside bond of mannose is formed.
Another significant patent involves a mass spectrometer and a method for analyzing isomers. This invention seeks to determine the presence ratio between mixed compounds that are challenging to separate and cannot be discriminated by mass spectrometry (MS). The mass spectrometer includes an MS analysis function for ionizing a sample, fragmenting an ion of a desired mass number, and performing mass analysis of fragment ions. It also features a database that stores correlation information between isomer presence ratios and specific ion intensity ratios in a mass spectrum per isomer. This innovation allows for the clarification of isomer ratios, even for mixed samples of isomers, such as enantiomers.
Career Highlights
Throughout his career, Yasuhiro Takegawa has worked with prominent companies, including Hitachi High-Technologies Corporation and Shionogi Company Limited. His experience in these organizations has contributed to his expertise in the field of biochemistry and analytical techniques.
Collaborations
Takegawa has collaborated with notable coworkers, including Izumi Ogata and Shinya Ito. Their joint efforts have furthered research and development in their respective areas of expertise.
Conclusion
Yasuhiro Takegawa's innovative work in glycoprotein synthesis and mass spectrometry has made a significant impact in the scientific community. His patents reflect a commitment to advancing technology and understanding in these complex fields.