Yang Hsia

Title: Innovations of Yang Hsia in Protein Nanostructures

Introduction

Yang Hsia is a prominent inventor based in Seattle, WA, known for his significant contributions to the field of protein nanostructures. He holds three patents that showcase his innovative approach to biochemistry and molecular biology. His work has implications for various applications, particularly in the medical and pharmaceutical fields.

Latest Patents

One of Yang Hsia's latest patents is focused on self-assembling protein nanostructures that display paramyxovirus and/or pneumovirus F proteins. This patent discloses nanostructures that include polypeptide assemblies and methods for their production. The application details multimeric assemblies comprising multiple oligomeric substructures, where each substructure includes proteins that self-interact around an axis of rotational symmetry. These proteins feature polypeptide-polypeptide interfaces and domains capable of effecting membrane scission, facilitating the release of enveloped multimeric assemblies from cells. The multimeric assembly also includes subunits that interact with lipid bilayers, enhancing their functionality.

Career Highlights

Yang Hsia has had a distinguished career, working at notable institutions such as the University of Washington and the University of Utah Research Foundation. His research has significantly advanced the understanding of protein interactions and their applications in nanotechnology.

Collaborations

Throughout his career, Yang Hsia has collaborated with esteemed colleagues, including Neil P. King and David Baker. These collaborations have further enriched his research and contributed to the development of innovative solutions in his field.

Conclusion

Yang Hsia's work in protein nanostructures exemplifies the intersection of innovation and practical application in science. His patents and collaborations highlight his role as a leading inventor in the field, paving the way for future advancements.