Xiaoyan Mo

Title: Innovations of Xiaoyan Mo in Vaccine Development

Introduction

Xiaoyan Mo is a prominent inventor based in Boxborough, MA (US), known for her significant contributions to the field of vaccine development. With a total of 2 patents, she has focused her research on innovative methods for the prevention and treatment of viral infections.

Latest Patents

One of her latest patents is titled "Vaccine for treatment and prevention of herpes simplex virus infection." This invention relates to methods and compositions designed to prevent and treat herpes virus infections. It provides antigenic peptides and pharmaceutical compositions that comprise complexes of these peptides and adjuvants, which can activate an immune response against herpes viruses. The invention also details methods for producing the antigenic peptides and their complexes, along with methods of using the pharmaceutical compositions.

Another notable patent is "Fusogenic, self-propagating blebs as immunogenic compositions." This invention involves the production of self-propagating, fusogenic blebs from cells infected with Venezuelan Equine Encephalitis virus replicon particles (VRP). The blebs are created through the expression of heterologous genes encoding viral fusion proteins, which are incorporated into replication-defective replicon particles. These blebs can be harvested from supernatants of cells exhibiting severe cytopathic effects and are utilized to create immunogenic compositions for immunizing mammals against paramyxoviruses, such as parainfluenza virus type 3.

Career Highlights

Xiaoyan Mo has worked with notable companies in the biotechnology sector, including Agenus Inc. and Wyeth Holdings Corporation. Her work in these organizations has contributed to advancements in vaccine technology and immunology.

Collaborations

Some of her coworkers include Alemseged Truneh and Daniel Lewis Levey, who have collaborated with her on various projects related to vaccine development.

Conclusion

Xiaoyan Mo's innovative work in vaccine development has led to significant advancements in the prevention and treatment of viral infections. Her contributions continue to impact the field of immunology and public health.