North Brunswick, NJ, United States of America

Xiaoxiang Zhu

USPTO Granted Patents = 6 


 

Average Co-Inventor Count = 5.2

ph-index = 3

Forward Citations = 52(Granted Patents)


Location History:

  • North Brunswick, NJ (US) (2010 - 2014)
  • Cranbury, NJ (US) (2015 - 2023)

Company Filing History:


Years Active: 2010-2023

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6 patents (USPTO):Explore Patents

Title: Inventor Xiaoxiang Zhu: Pioneering Advances in Pompe Disease Treatment

Introduction

Xiaoxiang Zhu, an innovative inventor based in North Brunswick, NJ, has made significant contributions to the field of biopharmaceuticals. With a total of six patents to his name, Zhu is at the forefront of developing treatments for debilitating conditions, particularly Pompe disease.

Latest Patents

Zhu's latest patents focus on methods for the treatment of Pompe disease using derivatives of 1-deoxynojirimycin. These inventions describe techniques to enhance the activity of both mutant and wild-type α-glucosidase enzymes, offering hope for improved therapeutic options. Specifically, the patents detail a method that involves the administration of pharmacological chaperones that are derivatives of 1-deoxynojirimycin. These chaperones are designed to increase enzyme activity in vitro and in vivo, and they can be substituted at the N or C1 position. Moreover, Zhu's inventions explore combination therapies that include replacement α-glucosidase genes or enzymes, adding a layer of versatility to treatment strategies.

Career Highlights

Throughout his career, Xiaoxiang Zhu has made notable strides while working with leading companies in the biopharmaceutical industry. He has been associated with Amicus Therapeutics, Inc. and P2D, Inc., where his research has focused on therapeutic advancements for rare genetic diseases. His expertise in enzyme therapies has positioned him as a key player in the fight against Pompe disease, a condition that arises from the deficiency of a specific enzyme.

Collaborations

Zhu has collaborated with prominent figures in the field, such as Kamlesh A Sheth and Nigel H Greig. These partnerships have helped foster research advancements and innovative solutions for genetic disorders, enhancing the overall impact of their collective work.

Conclusion

Xiaoxiang Zhu's contributions to the scientific community, especially through his patents on Pompe disease treatments, showcase his commitment to improving lives through innovation. His work exemplifies the potential of targeted therapies and highlights the importance of collaborative efforts in scientific research. As he continues to innovate, Zhu remains a crucial figure in the development of effective treatments for complex diseases.

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