The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 01, 2013
Filed:
Jun. 03, 2011
Nigel H. Greig, Phoenix, MD (US);
Harold Holloway, Middle River, MD (US);
Arnold Brossi, Bethesda, MD (US);
Xiaoxiang Zhu, North Brunswick, NJ (US);
Tony Giordano, Shreveport, LA (US);
Qian-sheng Yu, Lutherville, MD (US);
William D. Figg, Fairfax, VA (US);
Nigel H. Greig, Phoenix, MD (US);
Harold Holloway, Middle River, MD (US);
Arnold Brossi, Bethesda, MD (US);
Xiaoxiang Zhu, North Brunswick, NJ (US);
Tony Giordano, Shreveport, LA (US);
Qian-sheng Yu, Lutherville, MD (US);
William D. Figg, Fairfax, VA (US);
P2D, Inc., Cincinnati, OH (US);
Abstract
Thalidomide analogs that modulate tumor necrosis factor alpha (TNF-α) activity and angiogenesis are disclosed. In particularly disclosed embodiments, the thalidomide analogs are isosteric sulfur-containing analogs. Also disclosed are methods of treating a subject with the analogs.