This inventor holds 11 USPTO granted patents and 4 published patent applications and 1 EPO patent. Top assignees: Wisconsin Alumni Research Foundation, Procella Therapeutics Ab, Lancell Ab. Active years: 2015-2023.
Location History:
- Dongtai, CN (2015 - 2016)
- Madison, WI (US) (2015 - 2017)
- Allston, MA (US) (2016 - 2017)
- University Park, PA (US) (2020)
- State College, PA (US) (2021)
- Solna, SE (2018 - 2023)
Company Filing History:
8 out of 4,235 
2 out of 8 
1 out of 1 Years Active: 2015-2023
Title: Innovations of Xiaojun Lance Lian
Introduction
Xiaojun Lance Lian is a prominent inventor based in University Park, PA (US). He has made significant contributions to the field of stem cell research, holding a total of 11 patents. His work focuses on methods for differentiating human pluripotent stem cells and developing advanced cell culture techniques.
Latest Patents
Among his latest patents, Lian has developed methods for epicardial differentiation of human pluripotent stem cells. These methods describe how to generate high-yield, high-purity epicardial cells by activating Wnt/β-catenin signaling in human cardiac progenitor cells. This activation can be achieved by inhibiting Gsk-3, which induces differentiation into epicardial cells. Additionally, he has provided methods for the long-term in vitro maintenance of these cells under chemically defined, xeno-free, and albumin-free culture conditions. Another notable patent involves a serum-free human pluripotent stem cell culture medium, which includes enriched basal media supplemented with ascorbic acid, a member of the fibroblast growth factor (FGF) superfamily, a transforming growth factor-beta (TGF-beta) superfamily ligand, and a stable glutamine source. This innovation allows for the extended culturing of stem cells and the development of related kits.
Career Highlights
Lian has worked with notable organizations such as the Wisconsin Alumni Research Foundation and Procella Therapeutics. His experience in these companies has contributed to his expertise in stem cell technology and regenerative medicine.
Collaborations
Some of his notable coworkers include Sean Paul Palecek and Timothy Joseph Kamp, who have collaborated with him on various research projects.
Conclusion
Xiaojun Lance Lian's innovative work in stem cell research and his numerous patents highlight his significant contributions to the field. His advancements in cell differentiation and culture techniques are paving the way for future developments in regenerative medicine.