The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 30, 2015

Filed:

Nov. 15, 2010
Applicants:

Timothy J. Kamp, Madison, WI (US);

Sean Palecek, Verona, WI (US);

Jianhua Zhang, Madison, WI (US);

Samira Azarin, Madison, WI (US);

Xiaojun Lian, Madison, WI (US);

Inventors:

Timothy J. Kamp, Madison, WI (US);

Sean Palecek, Verona, WI (US);

Jianhua Zhang, Madison, WI (US);

Samira Azarin, Madison, WI (US);

Xiaojun Lian, Madison, WI (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/00 (2006.01); C12N 5/077 (2010.01);
U.S. Cl.
CPC ...
C12N 5/0657 (2013.01); C12N 2506/02 (2013.01); C12N 2501/155 (2013.01); C12N 2501/16 (2013.01); C12N 2501/727 (2013.01); C12N 2506/45 (2013.01);
Abstract

Methods for culturing the pluripotent stem cells to undergo epithelial-to-mesenchymal transition and for generating high-yield, high-purity cardiomyocyte cultures from pluripotent stem cells are described. Pluripotent stem cells are cultured on a support with an overlaid matrix and, optionally, exposed to one or more factors to induce epithelial-to-mesenchymal transition and cardiogenesis.


Find Patent Forward Citations

Loading…