Samira M Azarin

Title: Samira M Azarin: Innovator in Blood-Brain Barrier Research

Introduction

Samira M Azarin is a prominent inventor based in Chicago, IL (US). She has made significant contributions to the field of biomedical engineering, particularly in the development of models for the human blood-brain barrier. With a total of 3 patents, her work is paving the way for advancements in neurological research and therapies.

Latest Patents

One of her latest patents is titled "Retinoic acid enhanced human stem cell derived blood brain barrier model." This invention outlines a method for creating a fully-human blood-brain barrier (BBB) model. The process involves obtaining a mixture of neural cells and brain microvascular endothelial cells (BMECs) derived from human pluripotent stem cells (hPSCs). The method includes purifying BMECs from this mixture and co-culturing them with other cell types such as pericytes, astrocytes, and differentiated neural progenitor cells (NPCs) to create a functional blood-brain barrier model. Another notable patent is "Human blood-brain barrier endothelial cells derived from pluripotent stem cells and blood-brain barrier model thereof," which discloses a model blood-brain barrier obtained from hPSCs.

Career Highlights

Samira M Azarin is affiliated with the Wisconsin Alumni Research Foundation, where she continues to innovate and contribute to her field. Her research focuses on creating more effective models for studying the blood-brain barrier, which is crucial for understanding various neurological conditions.

Collaborations

She has collaborated with notable colleagues such as Sean Paul Palecek and Eric V Shusta, enhancing the impact of her research through teamwork and shared expertise.

Conclusion

Samira M Azarin's work in developing human blood-brain barrier models represents a significant advancement in biomedical research. Her innovative patents and collaborations are set to influence future studies and therapies in neurology.