Xianzhao Kuang

Title: Innovations by Inventor Xianzhao Kuang

Introduction

Xianzhao Kuang is a renowned inventor based in Beijing, China, known for his significant contributions to the field of pharmaceutical sciences. With a total of two patents to his name, he specializes in the development of innovative compounds aimed at cancer treatment.

Latest Patents

Xianzhao Kuang's latest inventions include two notable patents. The first one, titled "Crystalline forms of salts of fused penta-cyclic dihydrodiazepinocarbazolones and uses thereof," discloses various crystalline forms (polymorphs) of a compound which is instrumental in treating cancers that respond to the inhibition of PARP, particularly those linked to BRCA1/2 mutations or other HR deficiencies. This patent also outlines methods for preparing these crystalline forms and their therapeutic applications.

The second patent, "Process for preparing a PARP inhibitor, crystalline forms, and uses thereof," details a process for creating a PARP1/2 inhibitor known as (R)-2-fluoro-10a-methyl-7,8,9,10,10a,11-hexahydro-5,6,7a,11-tetraazacyclohepta[def]cyclopenta[a]fluoren-4(5H)-one, referred to as Compound A. This document elaborates on the crystalline forms and methods for their preparation, as well as the application of these compounds in targeted cancer therapies.

Career Highlights

Xianzhao Kuang is currently a pivotal member of BeiGene, Ltd., a biotechnology company focused on innovative molecular oncology. His work centers around drug discovery and development, significantly impacting the advancement of cancer treatment methodologies.

Collaborations

Throughout his career, Xianzhao has collaborated with esteemed colleagues, including Hexiang Wang and Changyou Zhou. These partnerships have fostered a productive environment for innovation and research excellence at BeiGene.

Conclusion

In summary, Xianzhao Kuang stands out as a prominent figure in pharmaceutical innovation. His groundbreaking patents have the potential to transform cancer treatment and highlight the importance of ongoing research and collaboration in fighting this disease. His contributions continue to pave the way for future advancements in oncology.