The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 29, 2019
Filed:
Aug. 22, 2016
Applicant:
Beigene, Ltd., Camana Bay, Grand Cayman, KY;
Inventors:
Hexiang Wang, Beijing, CN;
Changyou Zhou, Princeton, NJ (US);
Bo Ren, Beijing, CN;
Xianzhao Kuang, Beijing, CN;
Assignee:
BEIGENE, LTD., Grand Cayman, KY;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/06 (2006.01); C07D 487/22 (2006.01); C07D 471/22 (2006.01); C07D 471/04 (2006.01); A61P 35/04 (2006.01);
U.S. Cl.
CPC ...
C07D 471/22 (2013.01); A61P 35/04 (2018.01); C07D 471/04 (2013.01); C07B 2200/13 (2013.01);
Abstract
Provided are a process for preparing a Parp1/2 inhibitor, i.e., (R)-2-fluoro-10a-methyl-7,8,9,10,10a,11-hexahydro-5,6,7a,11-tetraazacyclohepta[def]cyclopenta[a]fluoren-4(5H)-one (hereinafter referred to as Compound A), crystalline forms (poly-morphs) of Compound A or hydrate or solvate thereof, methods for preparing the crystalline forms, and the use thereof.