Company Filing History:
Years Active: 1998
Title: Innovations by William R Thomas
Introduction
William R Thomas is a notable inventor based in Laguna Niguel, California. He has made significant contributions to the field of medical technology, particularly in the development of fibrinogen-containing compositions. With a total of two patents to his name, his work has the potential to impact various medical applications.
Latest Patents
William R Thomas's latest patents include a method of preparing a topical fibrinogen complex. This method involves preparing a fibrinogen-containing composition derived from human plasma by separating a cryoprecipitate from the plasma. The process includes suspending the cryoprecipitate in a salt-containing buffer and treating the supernatant by affinity-chromatography on a lysine-bound solid matrix to allow plasminogen to adsorb. The resulting fraction contains less than 10 µg/ml plasminogen, and the treatment reduces viral activity. The fibrinogen-containing composition recovered from this fraction is advantageous because it contains such a low amount of plasminogen that no addition of fibrinolysis inhibitor is needed. Additionally, he has developed a topical fibrinogen complex that, upon reacting with thrombin, functions as a fibrin sealant. This composition is characterized as being free of detectable levels of lipid enveloped virus activity, free of prothrombin complex and active thrombin, and contains no protease inhibitors or other non-human proteins.
Career Highlights
William R Thomas is currently associated with Baxter International Inc., a leading company in the healthcare sector. His work at Baxter has allowed him to focus on innovative solutions that enhance patient care and safety.
Collaborations
Some of his notable coworkers include Daphne C Tse and Samia S Mankarious. Their collaborative efforts contribute to the advancement of medical technologies and innovations.
Conclusion
William R Thomas is a distinguished inventor whose work in developing fibrinogen-containing compositions has the potential to revolutionize medical treatments. His contributions to Baxter International Inc. and the field of medical technology are commendable and reflect his dedication to innovation.