The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 11, 1998
Filed:
Jun. 06, 1995
Daphne C Tse, Duarte, CA (US);
Samia S Mankarious, Costa Mesa, CA (US);
Shu Len Liu, Cerritos, CA (US);
William R Thomas, Laguna Nigel, CA (US);
Melaine Alpern, Long Beach, CA (US);
Stanley T Enomoto, Van Nuys, CA (US);
Cataline M Garanchon, Northridge, CA (US);
Baxter International Inc., Deerfield, IL (US);
Abstract
A method for preparing a fibrinogen-containing composition derived from human plasma by separating a cryoprecipitate from the plasma, suspending the cryoprecipitate in a salt-containing buffer, treating the supernatant by affinity-chromatography on a lysine-bound solid matrix to allow plasminogen to adsorb thereon, collecting a fraction containing less than 10 .mu.g/ml plasminogen, and treating the fraction to reduce viral activity. The fibrinogen-containing composition recovered from this fraction is advantageous because it contains such a low amount of plasminogen that no addition of fibrinolysis inhibitor is needed.