Company Filing History:
Years Active: 1998
Title: The Innovations of Samia S Mankarious
Introduction
Samia S Mankarious is an accomplished inventor based in Costa Mesa, CA (US). He has made significant contributions to the field of medical technology, particularly in the development of fibrinogen-based compositions. With a total of 2 patents, Mankarious has demonstrated a commitment to advancing healthcare solutions.
Latest Patents
Mankarious's latest patents include a method of preparing a topical fibrinogen complex. This innovative method involves preparing a fibrinogen-containing composition derived from human plasma by separating a cryoprecipitate from the plasma. The process includes suspending the cryoprecipitate in a salt-containing buffer and treating the supernatant through affinity-chromatography on a lysine-bound solid matrix. This allows plasminogen to adsorb, leading to the collection of a fraction containing less than 10 µg/ml plasminogen, which is then treated to reduce viral activity. The resulting fibrinogen-containing composition is advantageous due to its low plasminogen content, eliminating the need for additional fibrinolysis inhibitors. Another notable patent is the topical fibrinogen complex, which reacts with thrombin to function as a fibrin sealant. This composition is characterized by being free of detectable levels of lipid-enveloped virus activity, prothrombin complex, active thrombin, and contains no protease inhibitors or other non-human proteins.
Career Highlights
Mankarious is currently employed at Baxter International Inc., a leading company in the healthcare sector. His work focuses on developing innovative solutions that enhance patient care and treatment outcomes. His expertise in fibrinogen-based technologies has positioned him as a key contributor to advancements in medical treatments.
Collaborations
Mankarious has collaborated with notable colleagues, including Daphne C Tse and Shu Len Liu. These partnerships have fostered a collaborative environment that encourages innovation and the sharing of ideas.
Conclusion
Samia S Mankarious is a prominent inventor whose work in fibrinogen-based compositions has the potential to revolutionize medical treatments. His contributions to the field highlight the importance of innovation in healthcare.