Company Filing History:
Years Active: 1992-1998
Title: Melaine Alpern: Innovator in Fibrinogen Technology
Introduction
Melaine Alpern is a notable inventor based in Long Beach, California. She has made significant contributions to the field of medical technology, particularly in the development of fibrinogen-based compositions. With a total of three patents to her name, Alpern's work has the potential to impact various medical applications.
Latest Patents
Alpern's latest patents include a method of preparing a topical fibrinogen complex. This innovative method involves preparing a fibrinogen-containing composition derived from human plasma by separating a cryoprecipitate from the plasma. The process includes suspending the cryoprecipitate in a salt-containing buffer and treating the supernatant through affinity-chromatography on a lysine-bound solid matrix. This allows plasminogen to adsorb, leading to the collection of a fraction containing less than 10 µg/ml plasminogen, which is then treated to reduce viral activity. The resulting fibrinogen-containing composition is advantageous due to its low plasminogen content, eliminating the need for additional fibrinolysis inhibitors.
Another significant patent is the topical fibrinogen complex, which reacts with thrombin to function as a fibrin sealant. This composition is characterized by being free of detectable levels of lipid-enveloped virus activity, prothrombin complex, and active thrombin. It also contains no protease inhibitors or other non-human proteins, showcasing Alpern's commitment to safety and efficacy in her inventions.
Career Highlights
Melaine Alpern is currently employed at Baxter International Inc., a leading company in the healthcare sector. Her work at Baxter has allowed her to focus on innovative solutions that enhance patient care and treatment outcomes.
Collaborations
Alpern collaborates with talented professionals in her field, including Daphne C Tse and Samia S Mankarious. These collaborations foster a creative environment that encourages the development of groundbreaking medical technologies.
Conclusion
Melaine Alpern's contributions to fibrinogen technology exemplify her dedication to advancing medical science. Her innovative patents and work at Baxter International Inc. highlight her role as a key player in the healthcare industry. Alpern's inventions have the potential to significantly improve medical treatments and patient outcomes.