William Kelton

Title: The Innovative Contributions of William Kelton

Introduction

William Kelton is a notable inventor based in Austin, TX, who has made significant contributions to the field of biotechnology. With a total of three patents to his name, Kelton's work primarily focuses on engineered antibodies and immunoglobulin Fc domains. His innovative approaches have the potential to advance therapeutic applications in medicine.

Latest Patents

Kelton's latest patents include groundbreaking work on antibodies with engineered IgG Fc domains. These antibodies are designed to efficiently bind to both Fcγ and Fcα receptors, enhancing their effectiveness in therapeutic applications. One of his notable inventions involves a chimeric IgG CH2 domain that incorporates an α1 loop from IgA, along with an IgA CH3 domain. Additionally, he has developed engineered immunoglobulin Fc polypeptides that feature aglycosylated antibody Fc domains. These polypeptides can selectively bind to certain Fc receptors, promoting antibody-dependent cell-mediated toxicity (ADCC) through innovative methods and compositions.

Career Highlights

Throughout his career, William Kelton has worked with esteemed organizations such as the Research Development Foundation and the University of Texas System. His experience in these institutions has allowed him to collaborate on various research projects, furthering the understanding of antibody engineering and its applications.

Collaborations

Kelton has collaborated with notable colleagues, including George Georgiou and Sang Taek Jung. These partnerships have contributed to the advancement of his research and the development of innovative solutions in the field of biotechnology.

Conclusion

William Kelton's contributions to the field of biotechnology through his patents and collaborations highlight his role as a leading inventor. His work on engineered antibodies and immunoglobulin Fc domains has the potential to significantly impact therapeutic strategies in medicine.