The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 13, 2018
Filed:
Aug. 30, 2013
Applicant:
The Board of Regents of the University of Texas System, Austin, TX (US);
Inventors:
Assignee:
Board of Regents, The University of Texas System, Austin, TX (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/30 (2006.01); C07K 16/32 (2006.01); C07K 16/28 (2006.01); A61K 47/48 (2006.01); C07K 16/00 (2006.01); A61K 47/68 (2017.01);
U.S. Cl.
CPC ...
C07K 16/2863 (2013.01); A61K 47/48561 (2013.01); A61K 47/6849 (2017.08); C07K 16/00 (2013.01); C07K 16/30 (2013.01); C07K 16/32 (2013.01); C07K 2317/52 (2013.01); C07K 2317/524 (2013.01); C07K 2317/56 (2013.01); C07K 2317/66 (2013.01); C07K 2317/71 (2013.01); C07K 2317/72 (2013.01); C07K 2317/732 (2013.01); C07K 2317/92 (2013.01);
Abstract
Antibody Fc polypeptides are provided that efficiently bind to both Fcγ and Fcα receptors. In certain aspects, a Fc polypeptide comprises a chimeric IgG CH2 domain having a α1 loop from IgA and an IgA CH3 domain. Recombinant antibodies comprising Fc polypeptides of the embodiments and methods for making and using such antibodies are likewise provided.