Wen Shi

Title: Innovations and Contributions of Inventor Wen Shi

Introduction

Wen Shi is an accomplished inventor based in San Francisco, CA, known for his significant contributions to the field of medical research. With a total of two patents to his name, he has focused on developing innovative therapeutic methods for treating serious health conditions, particularly pancreatic cancer.

Latest Patents

Wen Shi's latest patents include a therapeutic method for pancreatic cancer, which relates to methods and medicaments useful for treating locally advanced pancreatic cancer (LAPC). This invention provides improved therapeutic methods and regimens comprising anti-connective tissue growth factor (CTGF) agents, including anti-CTGF antibodies. The patent also includes induction therapies aimed at converting unresectable LAPC into borderline or resectable status. Another notable patent involves human RRP sequences and methods of use, which detail Rhomboid Related Proteins (RRPs) that are involved in the EGFR signaling pathway. This patent describes transgenic, nonhuman mammals containing a transgene encoding an RRP polypeptide, along with methods for modulating the interaction of RRP proteins with their pathway members.

Career Highlights

Throughout his career, Wen Shi has worked with prominent companies such as Fibrogen, Inc. and Exelixis, Inc. His work has significantly impacted the development of new therapeutic strategies in oncology, particularly in the context of pancreatic cancer treatment.

Collaborations

Wen Shi has collaborated with notable professionals in his field, including Katharina Modelska and Frank Valone. These collaborations have contributed to the advancement of his research and the successful development of his patented technologies.

Conclusion

Wen Shi's innovative work and patents reflect his dedication to improving cancer treatment methodologies. His contributions to medical research continue to pave the way for advancements in therapeutic approaches for challenging diseases.