The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 25, 2017
Filed:
Jan. 09, 2015
Applicant:
Fibrogen, Inc., San Francisco, CA (US);
Inventors:
Katharina Modelska, Millbrae, CA (US);
Frank Valone, Mill Valley, CA (US);
Vincent Picozzi, Mercer-Island, WA (US);
Wen Shi, San Francisco, CA (US);
Assignee:
FIBROGEN, INC., San Francisco, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); C07K 16/22 (2006.01); A61K 31/713 (2006.01); A61K 45/06 (2006.01); A61K 31/7068 (2006.01); A61K 31/337 (2006.01); A61K 47/48 (2006.01); A61B 10/04 (2006.01); C12N 15/113 (2010.01); A61K 39/00 (2006.01); A61N 5/10 (2006.01);
U.S. Cl.
CPC ...
C07K 16/22 (2013.01); A61B 10/04 (2013.01); A61K 31/337 (2013.01); A61K 31/7068 (2013.01); A61K 31/713 (2013.01); A61K 39/3955 (2013.01); A61K 45/06 (2013.01); A61K 47/48284 (2013.01); A61K 47/48884 (2013.01); C12N 15/1136 (2013.01); A61K 2039/505 (2013.01); A61K 2039/54 (2013.01); A61K 2039/545 (2013.01); A61N 2005/1098 (2013.01); C07K 2317/76 (2013.01); C12N 2310/11 (2013.01); C12N 2310/14 (2013.01); C12N 2310/141 (2013.01); C12N 2310/531 (2013.01);
Abstract
The present invention relates to methods and medicarnents useful for treating locally advanced pancreatic cancer (LAPC). Improved therapeutic methods and regimens comprising anti-connective tissue growth factor (CTGF) agents, including anti-CTGF antibodies, are provided. Included are induction therapies for converting unreseetable LAPC into borderline or resectable status.