Warren Charles Kett

Title: Warren Charles Kett: Innovator in Glycobiology

Introduction

Warren Charles Kett is a notable inventor based in West Lebanon, NH (US), recognized for his contributions to glycobiology. He holds a total of six patents, showcasing his innovative approach to addressing complex biological challenges.

Latest Patents

One of his latest patents is titled "Anionic conjugates of glycosylated bacterial metabolite." This invention relates to anionic conjugates of glycosylated bacterial metabolites that may be used to mimic the structure and/or activity of the anionic bioactive molecules known as glycosaminoglycans (GAGs). The invention also encompasses processes for the preparation of these conjugates, which are useful in the prophylaxis and/or treatment of various disease conditions, particularly chronic diseases such as inflammatory diseases, metastatic cancers, and infections by pathogenic agents including bacteria, viruses, or parasites. Another significant patent is "Production of glycoproteins with reduced O-glycosylation." This method describes producing protein compositions with reduced amounts of O-linked glycosylation by culturing cells in the presence of an inhibitor of Pmt-mediated O-linked glycosylation and/or in the presence of one or more α-1,2-mannosidases.

Career Highlights

Throughout his career, Kett has worked with prominent companies in the field, including Glycofi, Incorporated and Glycan Biosciences LLC. His work has significantly advanced the understanding and application of glycosylation in therapeutic contexts.

Collaborations

Kett has collaborated with esteemed colleagues such as Piotr Bobrowicz and W. James Cook, contributing to a rich exchange of ideas and innovations in glycobiology.

Conclusion

Warren Charles Kett's innovative work in glycobiology and his numerous patents reflect his commitment to advancing medical science. His contributions continue to influence the field and offer potential solutions for various health challenges.