Wai-Leung Ng

Title: Innovations by Wai-Leung Ng

Introduction

Wai-Leung Ng is a prominent inventor based in Lawrenceville, NJ (US). He has made significant contributions to the field of bacterial pathogenicity and quorum sensing. With a total of 2 patents, his work focuses on developing novel anti-infectives and strategies to manipulate bacterial behavior.

Latest Patents

Ng's latest patents include "Broad spectrum pro-quorum-sensing molecules as inhibitors of virulence in vibrios." This patent describes the identification of eleven molecules that activate quorum sensing (QS), with eight acting as receptor agonists and three as antagonists of LuxO. These pro-QS molecules are pivotal for the development of new anti-infectives. Another notable patent is "Identification of bacterial autoinducer and use in treating bacterial pathogenicity." This work involves the purification and structural identification of a bacterial autoinducer, CAI-1, along with methods for synthesizing the autoinducer and its analogues. The patent outlines strategies for using these compounds to treat bacterial pathogenicity and biofilm formation, including methods for preventing and treating cholera.

Career Highlights

Wai-Leung Ng is affiliated with Princeton University, where he conducts his research. His innovative work has garnered attention in the scientific community, particularly in the areas of microbiology and infectious diseases.

Collaborations

Ng has collaborated with notable scientists such as Bonnie L. Bassler and Martin F. Semmelhack. These collaborations have further enhanced the impact of his research in the field.

Conclusion

Wai-Leung Ng's contributions to the understanding of bacterial quorum sensing and pathogenicity are invaluable. His innovative patents and research efforts continue to pave the way for advancements in anti-infective therapies.