Company Filing History:
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Title: **Vivian O'Donnell: A Pioneer in Vaccine Development**
Introduction
Vivian O'Donnell, based in Old Saybrook, Connecticut, is a prominent inventor specializing in the field of veterinary virology. With a remarkable portfolio of five patents, O'Donnell has made significant contributions to the development of vaccines for viral diseases affecting swine.
Latest Patents
O'Donnell's latest patents focus on innovative approaches to vaccine development against classical swine fever virus (CSFV) and African swine fever virus (ASFV). The first patent emphasizes a live attenuated classical swine fever vaccine created through genetic manipulation of a crucial fusion peptide area within the virus's structural glycoprotein E2. This groundbreaking research reveals how specific amino acid substitutions in the E2 region can impact viral replication and virulence in swine. Notably, the mutated virus, referred to as FPi.c, demonstrated complete attenuation and provided protection against virulent challenges in vaccinated animals.
The second patent addresses the urgent need for an effective vaccine against African swine fever, a disease that has devastated pig populations. This patent describes a recombinant 9GL/UK virus derived from the highly virulent ASFV Georgia 2007 isolate. The deletion of specific virulence-associated genes results in a virus strain that does not cause disease in swine and offers solid protection against subsequent exposure to the parental strain.
Career Highlights
O'Donnell has had a distinguished career, working with notable organizations such as the United States Department of Agriculture and the University of Connecticut. His expertise in veterinary science and virology has positioned him as a leader in developing innovative solutions for infectious diseases affecting livestock.
Collaborations
Throughout his career, O'Donnell has collaborated with esteemed colleagues, including Manuel V. Borca and Lauren G. Holinka-Patterson. These partnerships have been instrumental in advancing research and commercialization efforts related to swine health.
Conclusion
Vivian O'Donnell stands out as a key figure in the advancement of veterinary vaccines, particularly in the fight against classical and African swine fevers. His innovative patents and collaborative efforts have the potential to significantly impact the swine industry and enhance biosecurity measures for animal health.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.