Company Filing History:
4 out of 363 
4 out of 2,079 
2 out of 144 
Years Active: 2000-2010
Title: Virginia L Pulito: Innovator in Anticoagulant Antibodies
Introduction
Virginia L Pulito is a prominent inventor based in Flemington, NJ (US). She has made significant contributions to the field of biomedical research, particularly in the development of innovative antibodies for therapeutic use. With a total of 10 patents, her work has had a profound impact on the treatment of thrombotic diseases.
Latest Patents
Among her latest inventions are the CDR-grafted anti-tissue factor antibodies and methods of use thereof. This invention provides CDR-grafted antibodies against human tissue factor that retain the high binding affinity of rodent monoclonal antibodies against tissue factor but have reduced immunogenicity. The present humanized antibodies are potent anticoagulants and are thus useful in the treatment and prophylaxis of human thrombotic disease. The invention also includes methods of making the CDR-grafted antibodies and pharmaceutical compositions for the attenuation or prevention of coagulation.
Career Highlights
Virginia has worked with notable companies such as Ortho-McNeil Pharmaceutical Corporation and Janssen Pharmaceutica NV. Her experience in these organizations has allowed her to develop and refine her innovative ideas in the pharmaceutical industry.
Collaborations
Throughout her career, Virginia has collaborated with esteemed colleagues, including George Chiu and Peter J Connolly. These partnerships have contributed to her success and the advancement of her research.
Conclusion
Virginia L Pulito is a trailblazer in the field of anticoagulant antibodies, with a strong portfolio of patents that reflect her innovative spirit and dedication to improving human health. Her contributions continue to influence the development of effective treatments for thrombotic diseases.