Company Filing History:
2 out of 15 
1 out of 1 Years Active: 2013-2023
Title: Veronika Stepankova: Innovator in Protein Thermostabilization
Introduction
Veronika Stepankova is a prominent inventor based in Slavkov u Brna, Czech Republic. She has made significant contributions to the field of protein research, particularly in the area of thermostabilization and its applications in cell biology and regenerative medicine. With a total of 2 patents, her work is paving the way for advancements in medical and cosmetic applications.
Latest Patents
One of her latest patents is titled "Thermostable FGF2 polypeptide, use thereof." This invention provides an isolated thermostable polypeptide that possesses FGF2 activity, with at least 85% sequence identity to SEQ ID NO: 2 (FGF2 wt) or a functional fragment thereof. It includes at least one amino acid substitution R31L and is applicable in cell biology research, regenerative medicine, and related medical applications or cosmetics. Additionally, it discloses a culture medium comprising subjected FGF2 suitable for culturing human pluripotent stem cells, including both human embryonic stem cells and induced pluripotent stem cells.
Another significant patent is the "Method of thermostabilization of a protein and/or stabilization towards organic solvents." This method involves the thermostabilization of a protein that contains access routes, where at least one amino acid in the bottleneck of the access route is mutated. The process includes identifying the amino acids of the bottleneck and those that control the exchange of solvent between a buried protein core and the surrounding environment. The modifications aim to improve the packing of amino acids inside the access route, preventing undesired solvent molecules from reaching the protein core while allowing necessary compounds to pass through.
Career Highlights
Veronika has worked with notable institutions such as Masaryk University and Enantis s.r.o., where she has contributed her expertise in protein research and development. Her innovative approaches have garnered attention in the scientific community, leading to advancements in various applications.
Collaborations
Throughout her career, Veronika has collaborated with esteemed colleagues, including Jiri Damborsky and Zbynek Prokop. These partnerships have further enhanced her research and contributed to the success of her inventions.
Conclusion
Veronika Stepankova is a trailblazer in the field of protein thermostabilization, with her
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