Location History:
- Carlsbad, CA (US) (2002 - 2005)
- Oceanside, CA (US) (2008 - 2018)
- Los Angeles, CA (US) (2019)
- Lo Jolla, CA (US) (2019)
- La Jolla, CA (US) (2020 - 2021)
Company Filing History:
17 out of 1,187 
4 out of 15,475 
1 out of 607 Years Active: 2002-2021
Title: Innovations and Contributions of Valery Fokin
Introduction
Valery Fokin, an accomplished inventor based in Oceanside, CA, has made significant contributions to the field of chemical and pharmaceutical innovations. With a remarkable portfolio of 19 patents, his work primarily focuses on antidotes for organophosphate exposure and related technologies that enhance human health and safety.
Latest Patents
Fokin's latest patents include "Centrally active and orally bioavailable antidotes for organophosphate exposure and methods for making and using them." This innovative invention provides nucleophilic hydroxyimino-acetamido alkylamine antidotes designed to cross the blood-brain barrier (BBB). These compounds catalyze the hydrolysis of organophosphate (OP)-inhibited human acetylcholinesterase (hAChE) in the central nervous system (CNS). The design of these hydroxyimino-acetamido alkylamines aims to fit within the AChE active center gorge dimensions, ensuring efficient binding and reactivity with the conjugated phosphate atom. Additionally, the invention encompasses a range of delivery systems including pumps, subcutaneous infusion devices, and various types of injectors, which facilitate the administration of these compounds.
Career Highlights
Valery Fokin has worked with esteemed institutions such as The Scripps Research Institute and the University of California. His research and inventions have not only advanced scientific understanding but have also contributed significantly to public health initiatives.
Collaborations
Throughout his career, Fokin has collaborated with notable colleagues, including K Barry Sharpless, a Nobel Laureate in Chemistry, and Luke Green. These partnerships have spurred further innovations and enriched his work in the field of chemistry and pharmaceuticals.
Conclusion
Valery Fokin's work exemplifies the vital role of innovative thinking in addressing complex health challenges. His patents, particularly in antidote development, showcase the impact of targeted research and collaboration in creating solutions that can save lives and improve health outcomes. The ongoing advancements in his inventions continue to reshape the landscape of pharmaceutical sciences.