Uta Griesenbach

Title: Uta Griesenbach: Innovator in Gene Therapy

Introduction

Uta Griesenbach is a prominent inventor based in London, GB. She has made significant contributions to the field of gene therapy, particularly in the treatment of respiratory diseases. With a total of 2 patents, her work focuses on innovative methods for gene transfer using lentiviral vectors.

Latest Patents

Griesenbach's latest patents include groundbreaking inventions related to lentiviral gene transfer vectors. One patent describes lentiviral vectors pseudotyped with hemagglutinin-neuraminidase (HN) and fusion (F) proteins from a respiratory paramyxovirus. This invention comprises a promoter and a transgene, and it outlines methods for creating these vectors. The application of these vectors is particularly relevant for gene therapy aimed at treating respiratory tract diseases such as Cystic Fibrosis (CF). Another patent details the successful introduction of genes into stem cells of airway epithelial tissues using simian immunodeficiency virus vectors pseudotyped with F and HN proteins. This method is useful for gene therapy of genetic respiratory diseases, including cystic fibrosis, and allows for the selection of respiratory organs like the lungs as production tissues for deficient proteins.

Career Highlights

Throughout her career, Uta Griesenbach has worked with various companies, including Id Pharma Co., Ltd. and Ip2ipo Innovations Limited. Her expertise in gene therapy and innovative approaches to respiratory diseases has positioned her as a leading figure in her field.

Collaborations

Griesenbach has collaborated with notable coworkers such as Katsuyuki Mitomo and Makoto Inoue. These partnerships have contributed to her research and the advancement of her inventions.

Conclusion

Uta Griesenbach's contributions to gene therapy and her innovative patents highlight her role as a key inventor in the field. Her work continues to pave the way for advancements in the treatment of respiratory diseases.