The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 07, 2020

Filed:

Apr. 23, 2015
Applicants:

Ip2ipo Innovations Limited, London, GB;

ID Pharma Co., Ltd., Tsukuba-shi, JP;

Inventors:

Eric Walter Frederick Wolfgang Alton, London, GB;

Uta Griesenbach, London, GB;

Kamila Malgorzata Pytel, London, GB;

Michael Christian Paul-Smith, London, GB;

Ian Andrew Pringle, Oxford, GB;

Stephen Charles Hyde, Oxford, GB;

Deborah Rebecca Gill, Oxford, GB;

Lee Adrian Davies, Oxfordshire, GB;

Alan Christopher Boyd, Edinburgh, GB;

Gerard McLachlan, West Linton, GB;

Makoto Inoue, Tsukuba, JP;

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/86 (2006.01); A61K 38/37 (2006.01); A61K 48/00 (2006.01); C12N 7/00 (2006.01); C07K 14/47 (2006.01); C07K 14/755 (2006.01);
U.S. Cl.
CPC ...
C12N 15/86 (2013.01); A61K 38/37 (2013.01); A61K 48/0066 (2013.01); C07K 14/4712 (2013.01); C12N 7/00 (2013.01); C07K 14/755 (2013.01); C07K 2319/03 (2013.01); C07K 2319/33 (2013.01); C12N 2740/15032 (2013.01); C12N 2740/15043 (2013.01); C12N 2740/15045 (2013.01); C12N 2740/15051 (2013.01); C12N 2760/18845 (2013.01); C12N 2810/6072 (2013.01); C12N 2830/15 (2013.01);
Abstract

This invention relates to lentiviral gene transfer vectors pseudotyped with hemagglutinin-neuraminidase (HN) and fusion (F) proteins from a respiratory paramyxovirus, comprising a promoter and a transgene; and methods of making the same. The present invention also relates to the use of said vectors in gene therapy, particularly for the treatment of respiratory tract diseases such as Cystic Fibrosis (CF).


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