Location History:
- Singapore, SG (2021)
- Jurong Island, SG (2022)
Company Filing History:
3 out of 1,473 
1 out of 2,405 
1 out of 1 Years Active: 2021-2025
Title: Tsz Ying Yuen: Innovator in Cancer Therapeutics
Introduction
Tsz Ying Yuen is a notable inventor based in Singapore, recognized for his contributions to the field of cancer therapeutics. With a total of three patents to his name, Yuen has made significant strides in developing innovative compounds aimed at treating cancer.
Latest Patents
One of Yuen's latest patents is titled "Macrocyclic peptides as potent inhibitors of K-RAS G12D mutant." This invention provides compounds that can inhibit the G12D mutant of the Kirsten rat sarcoma (K-Ras) protein, which is crucial in cancer development. The compounds or their pharmaceutically acceptable salts are expected to serve as therapeutic agents for cancer treatment. Additionally, the invention includes pharmaceutical compositions that comprise these compounds and methods for their use in therapy and prophylaxis of cancer.
Another significant patent is the "Method of preparing stapled peptides." This patent describes an operationally simple, one-pot solid-supported preparation of saturated stapled peptides. The method utilizes ruthenium-catalyzed metathesis followed by solid-phase transfer hydrogenation using triethylhydrosilane at elevated temperatures. The utility of this method has been demonstrated on 14- and 16-mer peptides, yielding corresponding cyclic α-helix stabilized stapled peptides.
Career Highlights
Yuen has worked with prominent organizations such as the Agency for Science, Technology and Research and Merck Sharp & Dohme Corporation. His experience in these institutions has contributed to his expertise in the field of pharmaceutical sciences and innovation.
Collaborations
Throughout his career, Yuen has collaborated with notable individuals, including Charles William Johannes and Gerard Hilinski. These collaborations have likely enriched his research and development efforts in the pharmaceutical domain.
Conclusion
Tsz Ying Yuen stands out as an innovative inventor in the realm of cancer therapeutics, with a focus on developing effective treatments through his patented inventions. His work continues to have a significant impact on the field of medicine.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.