Company Filing History:
Years Active: 2004-2006
Title: Tony Kouzarides: Innovator in Histone Methylation and Transcription Regulation
Introduction
Tony Kouzarides is a prominent inventor based in Cambridge, GB. He has made significant contributions to the field of molecular biology, particularly in the areas of histone methylation and transcription regulation. With a total of three patents to his name, Kouzarides has established himself as a key figure in scientific research and innovation.
Latest Patents
Kouzarides' latest patents include groundbreaking work on methods and means of histone methylation. This invention focuses on a previously uncharacterized group of histone H3 methylases that play a crucial role in the methylation process. Specifically, these methylases are shown to be important for transcriptional activity, particularly through the trimethylation of lysine 4 within the amino tail of histone H3.
Another notable patent involves assays, methods, and means for modulating E2F activity. This research highlights the interaction between P/CAF and E2F, where the acetylation of E2F by P/CAF affects its ability to stimulate transcription. The modulation of this interaction has implications for cell growth disorders, oncogenicity, and apoptosis induction.
Career Highlights
Tony Kouzarides is currently associated with Chroma Therapeutics Limited, where he continues to advance his research and innovations. His work has garnered attention in the scientific community, contributing to a deeper understanding of cellular processes and potential therapeutic applications.
Collaborations
Kouzarides collaborates with notable researchers, including Helena Santos-Rosa, to further explore the complexities of histone modifications and their impact on gene expression.
Conclusion
Tony Kouzarides stands out as an influential inventor in the realm of molecular biology, with his patents paving the way for advancements in understanding histone methylation and transcription regulation. His contributions continue to shape the future of scientific research and innovation.