The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 10, 2005
Filed:
May. 17, 1999
Applicant:
Tony Kouzarides, Cambridge, GB;
Inventor:
Tony Kouzarides, Cambridge, GB;
Assignee:
Chroma Therapeutics Limited, Oxfordshire, GB;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q001/00 ; C12Q001/68 ; C12Q033/53 ;
U.S. Cl.
CPC ...
Abstract
P/CAF interacts with and acetylates E2F, this acetylation affecting ability of E2F to stimulate transcription. Interaction between P/CAF and E2F and acetylation of E2F by P/CAF are modulated, affecting ability of E2F to stimulate transcription, induction of S-phase in cells, oncogenicity of cells, and induction of apoptosis in cells. Agents are obtained for treatment of disorders of cell growth.