The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 08, 2004
Filed:
Jan. 25, 2001
Applicant:
Inventor:
Tony Kouzarides, Cambridge, GB;
Assignee:
Chroma Therapeutics Limited, London, GB;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 3/800 ; G01N 3/368 ; C12Q 1/48 ;
U.S. Cl.
CPC ...
A61K 3/800 ; G01N 3/368 ; C12Q 1/48 ;
Abstract
CBP histone acetyltransferase acetylates Importin &agr;, affecting ability of Importin &agr; to translate into the nucleus and import a cargo protein. Assays identify substances which modulate interaction between CBP and Importin &agr; and acetylation of Importin &agr; by CBP. Substances identified in the assays are useful for treatment of disorders in which Imporin &agr; plays a role.