Location History:
- Natick, MA (US) (1998 - 2010)
- Natic, MA (US) (2014)
- Sudbury, MA (US) (2004 - 2023)
Company Filing History:
14 out of 16 
14 out of 22 
8 out of 1,820 
Years Active: 1998-2025
Title: Inventions and Innovations of Tod M Woolf
Introduction
Tod M Woolf is a prominent inventor based in Sudbury, MA, known for his significant contributions to biotechnology. With a remarkable portfolio of 43 patents, he has made substantial advancements in the fields of RNA technology and antibody production.
Latest Patents
Among his latest patents is the innovative development of RNA duplexes with single stranded phosphorothioate nucleotide regions for additional functionality. This invention relates to RNA interference (RNAi) constructs and their applications in gene silencing. These constructs include a double-stranded region linked to a single-stranded region composed of phosphorothioate modified nucleotides, enhancing their utility in molecular biology.
Another notable patent reflects his work on antibody screening methods. This patent provides methods and compositions designed to produce novel antibodies that specifically bind to target antigens. These advances are particularly beneficial for generating antibodies that possess improved properties such as binding affinity, immunogenicity, and thermodynamic stability compared to reference antibodies.
Career Highlights
Tod M Woolf has collaborated with several companies during his career, including Rxi Pharmaceuticals Corporation and Phio Pharmaceuticals Corp. His experiences in these organizations have helped him develop groundbreaking solutions and innovations in the biopharmaceutical industry.
Collaborations
Throughout his career, Woolf has worked with distinguished colleagues such as Anastasia Khvorova and William Salomon. These collaborations have not only enhanced the scientific community’s understanding of RNA technologies and antibody development but also contributed to advancing therapeutic solutions in medicine.
Conclusion
Tod M Woolf’s contributions to innovation and invention in biotechnology underscore his role as a leading figure in the field. His numerous patents and collaborative works with reputable companies and fellow researchers highlight the impact of his work on future advancements in gene therapy and antibody production.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.