The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 21, 2020
Filed:
Jan. 21, 2019
Applicant:
Life Technologies Corporation, Carlsbad, CA (US);
Inventors:
Tod Woolf, Sudbury, MA (US);
Margaret Taylor, Hopkinton, MA (US);
Assignee:
LIFE TECHNOLOGIES CORPORATION, Carlsbad, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/113 (2010.01); C12N 15/11 (2006.01); A61K 31/713 (2006.01); C12N 5/00 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1137 (2013.01); A61K 31/713 (2013.01); C12N 15/111 (2013.01); C12N 15/113 (2013.01); C12N 15/1135 (2013.01); C12Y 207/11022 (2013.01); C12Y 301/03048 (2013.01); C12N 2310/11 (2013.01); C12N 2310/111 (2013.01); C12N 2310/14 (2013.01); C12N 2310/315 (2013.01); C12N 2320/11 (2013.01); C12N 2320/30 (2013.01); C12N 2320/31 (2013.01); C12N 2320/50 (2013.01); C12N 2330/30 (2013.01);
Abstract
The oligonucleotide compositions of the present invention make use of combinations of oligonucleotides. In one aspect, the invention features an oligonucleotide composition including at least 2 different oligonucleotides targeted to a target gene. This invention also provides methods of inhibiting protein synthesis in a cell and methods of identifying oligonucleotide compositions that inhibit synthesis of a protein in a cell.