The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 09, 2020
Filed:
Dec. 19, 2017
Applicant:
X-body, Inc., Waltham, MA (US);
Inventors:
Yan Chen, Lexington, MA (US);
Tod M. Woolf, Sudbury, MA (US);
Richard W. Wagner, Cambridge, MA (US);
Assignee:
X-BODY, INC., Waltham, MA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C40B 50/06 (2006.01); G01N 33/543 (2006.01); G01N 33/68 (2006.01); C07K 16/00 (2006.01); C07K 16/28 (2006.01); C40B 30/04 (2006.01);
U.S. Cl.
CPC ...
G01N 33/54306 (2013.01); C07K 16/005 (2013.01); C07K 16/2863 (2013.01); G01N 33/6854 (2013.01); C07K 2317/21 (2013.01); C07K 2317/56 (2013.01); C07K 2317/622 (2013.01); C40B 30/04 (2013.01); C40B 50/06 (2013.01);
Abstract
Provided are methods and compositions for the production of novel antibodies that bind specifically to a target antigen. These methods and compositions are particularly useful for producing antibodies having the antigen binding specificity of a reference antibody but with improved properties (e.g., binding affinity, immunogenicity, and thermodynamic stability) relative to the reference antibody.