Location History:
- Dallas, TX (US) (2003 - 2008)
- Broomfield, CO (US) (2004 - 2019)
Company Filing History:
4 out of 1,381 
4 out of 5,450 
1 out of 923 
Years Active: 2003-2019
Title: Innovations by Timothy McKinsey
Introduction
Timothy McKinsey is a prominent inventor based in Broomfield, CO (US). He has made significant contributions to the field of cardiac reprogramming, holding a total of 7 patents. His work focuses on the conversion of fibroblasts into cardiomyocytes, which has important implications for heart disease treatment.
Latest Patents
One of McKinsey's latest patents is titled "High efficiency reprogramming of fibroblasts into cardiomyocytes - Pro-fibrotic signaling potently antagonizes cardiac reprogramming." This patent discusses the inhibition of pro-fibrotic signaling using small molecules that target the transforming growth factor-β/SMAD or Rho kinase. This innovative approach leads to the conversion of approximately 60% of fibroblasts into beating cardiomyocytes. Furthermore, the disclosed methods allow for the conversion of fibroblasts to spontaneously contracting cardiomyocytes in less than two weeks.
Career Highlights
Throughout his career, Timothy McKinsey has worked with esteemed institutions such as the University of Colorado and the University of Texas System. His research has been pivotal in advancing our understanding of cardiac reprogramming and its potential applications in regenerative medicine.
Collaborations
Some of McKinsey's notable coworkers include Eric N Olson and Carlin Long. Their collaborative efforts have contributed to the success of his research and innovations in the field.
Conclusion
Timothy McKinsey's work in cardiac reprogramming represents a significant advancement in medical science. His innovative approaches and collaborations continue to pave the way for future breakthroughs in heart disease treatment.