Timothy Looney

Title: Innovations of Timothy Looney

Introduction

Timothy Looney is a prominent inventor based in Austin, TX, known for his significant contributions to the field of genomic data analysis. With a total of 12 patents to his name, he has made remarkable advancements in methods that enhance the understanding of immuno-oncology biomarkers.

Latest Patents

One of his latest patents is titled "Methods for context based compression of genomic data for immuno-oncology biomarkers." This innovative method involves compressing numbers of reads data for targeted genes of a gene expression assay performed on a test sample. The targeted genes are organized into categories, with each category representing a functional context associated with the targeted genes. The numbers of reads corresponding to targeted genes in each category are compressed to form a compressed value for that category. This compressed value is then compared to a baseline value to determine an enrichment or loss of a signature corresponding to the functional context. Additionally, the method may include analyzing information from multiple assays performed on the test sample, assigning a score value to each assay result, and predicting a response to immune-oncology treatment based on the assigned scores.

Another notable patent is "Dark cycle sequencing," which provides methods that include alternating series of sequencing cycles and dark extension cycles. This approach allows for longer read lengths and addresses the disadvantages of traditional nucleic acid sequencing protocols.

Career Highlights

Throughout his career, Timothy Looney has worked with notable companies such as Life Technologies Corporation and Singular Genomics Systems, Inc. His work has significantly impacted the field of genomic research and has paved the way for advancements in cancer treatment.

Collaborations

Timothy has collaborated with esteemed colleagues, including Eli N Glezer and Geoffrey Lowman, further enhancing the innovative work being done in his field.

Conclusion

Timothy Looney's contributions to genomic data analysis and immuno-oncology are noteworthy. His innovative patents and collaborations reflect his commitment to advancing scientific research and improving treatment methodologies.