The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 30, 2024
Filed:
Feb. 04, 2021
Applicant:
Life Technologies Corporation, Carlsbad, CA (US);
Inventors:
Assignee:
Life Technologies Corporation, Carlsbad, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C40B 50/06 (2006.01); C12Q 1/6811 (2018.01); C12Q 1/6844 (2018.01); C12Q 1/6869 (2018.01); C12Q 1/6876 (2018.01); C12Q 1/6881 (2018.01); C12Q 1/6883 (2018.01); C07K 14/725 (2006.01);
U.S. Cl.
CPC ...
C40B 50/06 (2013.01); C12Q 1/6811 (2013.01); C12Q 1/6844 (2013.01); C12Q 1/6869 (2013.01); C12Q 1/6876 (2013.01); C12Q 1/6881 (2013.01); C12Q 1/6883 (2013.01); C07K 14/7051 (2013.01); C12Q 2600/136 (2013.01); C12Q 2600/156 (2013.01); C12Q 2600/158 (2013.01); C12Q 2600/16 (2013.01); C12Q 2600/166 (2013.01);
Abstract
The present disclosure provides methods, compositions, kits, and systems useful in the determination and evaluation of the immune repertoire. In one aspect, target-specific primer panels provide for the effective amplification of sequences of T cell receptor and/or B cell receptor chains with improved sequencing accuracy and resolution over the repertoire. Variable regions associated with the immune cell receptor are resolved to effectively portray clonal diversity of a biological sample and/or differences associated with the immune cell repertoire of a biological sample.