The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 21, 2023

Filed:

Apr. 17, 2020
Applicant:

Life Technologies Corporation, Carlsbad, CA (US);

Inventors:

Fiona Hyland, San Mateo, CA (US);

Asha Kamat, San Bruno, CA (US);

Timothy Looney, Austin, TX (US);

Assignee:

Life Technologies Corporation, Carlsbad, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G16B 20/20 (2019.01); G06F 16/2457 (2019.01); G06F 16/248 (2019.01); G06N 3/126 (2023.01);
U.S. Cl.
CPC ...
G16B 20/20 (2019.02); G06F 16/248 (2019.01); G06F 16/24575 (2019.01); G06N 3/126 (2013.01);
Abstract

The method includes compressing numbers of reads data for targeted genes of a gene expression assay performed on a test sample. The targeted genes are organized into categories. Each category represents a functional context associated with the targeted genes in that category. The numbers of reads corresponding to targeted genes each category is compressed to form a compressed value for the category. The compressed value is compared to a baseline value for the category to determine an enrichment or a loss of a signature corresponding to the functional context of the category. The method may include analyzing information from multiple assays performed on the test sample, assigning a score value to each assay result and predicting a response to immune-oncology treatment based on the assigned scores.


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