Hockessin, DE, United States of America

Timothy C Burn

USPTO Granted Patents = 17 


Average Co-Inventor Count = 5.6

ph-index = 6

Forward Citations = 89(Granted Patents)


Location History:

  • Northborough, MA (US) (1997 - 2005)
  • Hockessin, DE (US) (2001 - 2022)

Company Filing History:


Years Active: 1997-2022

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17 patents (USPTO):

Title: Inventor Spotlight: Timothy C. Burn

Introduction

Timothy C. Burn is a notable inventor based in Hockessin, DE, USA, with a remarkable portfolio of 17 patents. His contributions to the field of pharmaceutical science are particularly significant, focusing on innovations that address critical medical challenges, including cancer treatment.

Latest Patents

Among his latest patents is a groundbreaking work on solid forms of an FGFR inhibitor. The patent details the compound 3-(2,6-difluoro-3,5-dimethoxyphenyl)-1-ethyl-8-(morpholin-4-ylmethyl)-1,3,4,7-tetrahydro-2H-pyrrolo[3',2':5,6]pyrido[4,3-d]pyrimidin-2-one, alongside its solid forms and polymorphs. This invention provides methods of preparation for these compounds, which are deemed useful in treating FGFR-associated diseases, particularly various forms of cancer.

Furthermore, he has developed another significant patent related to compositions, methods, and kits for Her-2 cleavage modulation. This invention leverages the ADAM-mediated cleavage of Her-2 to offer novel treatments for cancer, especially breast cancer. The invention showcases a synergistic effect between the inhibition of Her-2 cleavage with certain cytostatic and cytotoxic agents, aimed at inhibiting tumor cell proliferation and inducing cell death. Notably, it also includes the discovery of novel variants of ADAM15.

Career Highlights

Timothy Burn has a rich career, with experience in various esteemed organizations. He has notably worked at Genzyme Corporation, a company known for its focus on biopharmaceuticals and innovative therapies.

Collaborations

Throughout his career, Timothy has collaborated with other esteemed professionals in the field, including Gregory M. Landes and Timothy D. Connors. These collaborations have enabled him to enhance his work and innovate in significant ways while advancing scientific knowledge in biomedical research.

Conclusion

Timothy C. Burn's contributions to innovations in pharmaceuticals through his patents have paved the way for advancements in cancer treatment. His continued efforts in research and development make him a significant figure in the landscape of modern medicine.

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