The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 15, 2005
Filed:
Jun. 02, 1995
Katherine W. Klinger, Sudbury, MA (US);
Gregory M. Landes, Northborough, MA (US);
Timothy C. Burn, Northborough, MA (US);
Timothy D. Connors, Hopkinton, MA (US);
William Dackowski, Hopkinton, MA (US);
Gregory Germino, Baltimore, MD (US);
Feng Qian, Baltimore, MD (US);
Katherine W. Klinger, Sudbury, MA (US);
Gregory M. Landes, Northborough, MA (US);
Timothy C. Burn, Northborough, MA (US);
Timothy D. Connors, Hopkinton, MA (US);
William Dackowski, Hopkinton, MA (US);
Gregory Germino, Baltimore, MD (US);
Feng Qian, Baltimore, MD (US);
Genzyme Corporation, Cambridge, MA (US);
Johns Hopkins University, Baltimore, MD (US);
Abstract
The present invention provides methods and compositions for treating cyst formation in PKD1-associated epithelial cells. Such methods encompass administering an isolated human PKD1 gene, or fragments of the gene, under conditions that result in expression of therapeutically effective amounts of all, or part of, the PKD1 protein. The invention also encompasses compositions for treating cyst formation associated with APKD.