Location History:
- Northboro, MA (US) (2002 - 2003)
- Northborough, MA (US) (1997 - 2005)
- Livermore, CA (US) (2001 - 2005)
Company Filing History:
5 out of 787 
3 out of 3,682 
1 out of 1,644 
Years Active: 1997-2005
Title: Innovations and Contributions of Gregory M Landes
Introduction
Gregory M Landes is a notable inventor based in Northboro, MA (US), recognized for his significant contributions to the field of genetics and medical research. He holds a total of 10 patents, showcasing his innovative approach to addressing complex medical conditions.
Latest Patents
One of his latest patents involves KVLQT1, a gene associated with long QT syndrome. This patent discloses the genomic structure, including the sequence of the intron/exon junctions for KVLQT1 and KCNE1. It also reveals newly found mutations in KVLQT1 that result in long QT syndrome. The intron/exon junction sequence data enable the design of primer pairs to amplify and sequence across all exons of the two genes. This technology can be utilized to screen individuals for mutations causing long QT syndrome. Additionally, assays can be performed to detect mutations in either DNA or proteins, which may also be used to screen for drugs that could treat or prevent long QT syndrome.
Another significant patent pertains to polycystic kidney disease. This invention provides methods and compositions for treating cyst formation in PKD1-associated epithelial cells. The methods involve administering an isolated human PKD1 gene or its fragments, leading to the expression of therapeutically effective amounts of the PKD1 protein. This invention also includes compositions aimed at treating cyst formation associated with autosomal dominant polycystic kidney disease (APKD).
Career Highlights
Throughout his career, Gregory M Landes has worked with various organizations, including Genzyme Corporation. His work has significantly impacted the understanding and treatment of genetic disorders.
Collaborations
He has collaborated with notable professionals in the field, including Timothy C Burn and Timothy D Connors. Their joint efforts have contributed to advancements in genetic research and therapeutic applications.
Conclusion
Gregory M Landes is a distinguished inventor whose work in genetics has led to important innovations in the treatment of genetic disorders. His patents reflect a commitment to improving medical outcomes for patients with long QT syndrome and polycystic kidney disease.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.