Location History:
- Collingswood, NJ (US) (1980 - 1986)
- North Wales, PA (US) (1996 - 2016)
Company Filing History:
Years Active: 1980-2016
Title: Thomas R. Opie: An Innovator in Gene Expression
Introduction
Thomas R. Opie is a distinguished inventor based in North Wales, Pennsylvania, with an impressive portfolio of 10 patents. His innovative work primarily focuses on the modulation of gene expression, paving the way for advancements in genetic engineering and biotechnology.
Latest Patents
Among his most significant contributions are the patents related to bioavailable diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex. These inventions relate to non-steroidal ligands for use in nuclear receptor-based inducible gene expression systems. This method involves contacting an ecdysone receptor complex, composed of a DNA binding domain, a ligand binding domain, and a transactivation domain with a DNA construct that contains the exogenous gene alongside a response element. The innovative approach enables the regulation of the gene, resulting in either activation or suppression when the DNA binding domain interacts with the response element in the presence of the ligand.
Career Highlights
In his career, Thomas R. Opie has made significant strides through his employment with reputable companies such as Intrexon Corporation and Rohm and Haas Company. His contributions in these organizations have bolstered the development of innovative technologies within the biotechnology sector.
Collaborations
Throughout his journey, Thomas has collaborated with other notable professionals, including Robert Eugene Hormann and David W. Potter. These partnerships have played a vital role in the evolution of his work and the successful attainment of innovative solutions in gene expression modulation.
Conclusion
Thomas R. Opie's expertise and inventive spirit have made remarkable impacts on the fields of biotechnology and genetic research. With his continued dedication to innovation, he remains a pivotal figure in advancing understanding and applications of genetic engineering. His legacy, marked by his ten patents, continues to inspire future generations of inventors and researchers.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.