The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 25, 2008
Filed:
Feb. 26, 2004
Robert Eugene Hormann, Melrose Park, PA (US);
David W. Potter, North Wales, PA (US);
Orestes Chortyk, Thompson Station, TN (US);
Colin M. Tice, Elkins Park, PA (US);
Glenn Richard Carlson, North Wales, PA (US);
Andrew Meyer, Maple Glen, PA (US);
Thomas R. Opie, North Wales, PA (US);
Robert Eugene Hormann, Melrose Park, PA (US);
David W. Potter, North Wales, PA (US);
Orestes Chortyk, Thompson Station, TN (US);
Colin M. Tice, Elkins Park, PA (US);
Glenn Richard Carlson, North Wales, PA (US);
Andrew Meyer, Maple Glen, PA (US);
Thomas R. Opie, North Wales, PA (US);
Intrexon Corporation, Blacksburg, VA (US);
Abstract
The present invention relates to non-steroidal ligands for use in nuclear receptor-based inducible gene expression system, and a method to modulate exogenous gene expression in which an ecdysone receptor complex comprising: a DNA binding domain; a ligand binding domain; a transactivation domain; and a ligand is contacted with a DNA construct comprising: the exogenous gene and a response element; wherein the exogenous gene is under the control of the response element and binding of the DNA binding domain to the response element in the presence of the ligand results in activation or suppression of the gene.