Belmont, MA, United States of America

Thomas P Maniatis


Average Co-Inventor Count = 5.1

ph-index = 5

Forward Citations = 213(Granted Patents)


Location History:

  • Cambridge, MA (US) (1990)
  • Belmont, MA (US) (1998 - 2003)

Company Filing History:


Years Active: 1990-2003

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5 patents (USPTO):Explore Patents

Title: Thomas P Maniatis: Innovator in Molecular Biology

Introduction

Thomas P Maniatis is a prominent inventor based in Belmont, MA (US). He has made significant contributions to the field of molecular biology, particularly in the regulation of gene expression. With a total of 5 patents, his work has had a lasting impact on scientific research and applications.

Latest Patents

Among his latest patents, one notable invention is related to the regulation of NF-kB activity. This patent discloses a method for regulating the activity of NF-kB in an animal by contacting the cells with specific proteasome inhibitors. Another significant patent focuses on nuclear factors associated with transcriptional regulation. This invention describes constitutive and tissue-specific protein factors that bind to transcriptional regulatory elements of immunoglobulin genes. The factors were identified and isolated through an improved assay for protein-DNA binding, allowing for the enhancement of transcription of immunoglobulin genes.

Career Highlights

Throughout his career, Thomas P Maniatis has worked at prestigious institutions such as Harvard College and the Massachusetts Institute of Technology. His research has contributed to a deeper understanding of molecular mechanisms that govern gene expression and regulation.

Collaborations

Thomas has collaborated with notable scientists, including David Baltimore and Ranjan Sen. These collaborations have further enriched his research and expanded the impact of his inventions.

Conclusion

Thomas P Maniatis is a distinguished inventor whose work in molecular biology has led to important advancements in the understanding of gene regulation. His patents continue to influence research and applications in the field.

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